HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenyl isothiocyanate → HCID 86591805, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenyl isothiocyanate | HCID 15241 | — |
| Reactant | 7-Chloro-4-(piperazin-1-yl)quinoline | HCID 738389 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86591805 | HCID 86591805 | — |
Reaction Steps
7-Chloro-4-(piperazin-1-yl)quinoline (0.20 g, 0.8 mmol) and 4-fluorophenyl isothiocyanate (0.14 g, 0.9 mmol) in THF (10 mL) are reacted according to method C yielding the title product as a solid after column chromatography with hexane-EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-6e89973ba7fd42f7ba1ab9671ea5b9b4 |
| Source note | uspto-grants-2007_05 |