HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 21101973, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Fluorophenyl isothiocyanate | HCID 15241 | — |
| Reactant | O-Methylhydroxylamine hydrochloride | HCID 521874 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 21101973 | HCID 21101973 | 59.9% |
Reaction Steps
4-Fluorophenyl isothiocyanate (306 mg, 2.0 mmol), O-methyl hydroxylamine hydrochloride (835 mg, 10.0 mmol), and triethylamine (1.5 mL, 11.0 mmol) are stirred in THF-water (6 mL) for 2 h. The reaction mixture is diluted with ether, washed with water, dried (MgSO4), and concentrated yielding 240 mg of pale yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-0738220cd28f4b018c6be109c76379a7 |
| Source note | uspto-grants-2007_05 |