Diisopropylethylamine → HCID 178461367, compound

Participants

Reaction Steps

As described for example 78, cis-4-methyl-1-cyclohexanamine (170 mg, 1.5 mmol), 4-nitrophenyl chloroformate (302 mg, 1.5 mmol), diisopropyl(ethyl)amine (258 mg, 2 mmol), and 7-chloro-4-(piperazin-1-yl)quinoline (248 mg, 1 mmol) are reacted affording the title product after flash chromatography with CH2Cl2-MeOH. 1H NMR (DSMO-d6) δ 0.92 (d, 3H), 1.2 (m, 2H), 1.55–1.7 (m, 8H), 3.22 (m, 4H), 3.65 (m, 4H), 4.02 (br. s, 1H), 4.6 (m, 1H), 6.82 (d, 1H), 7.44 (d, 1H), 7.98 (d, 1H), 8.06 (s, 1), 8.78 (d, 1H).

Provenance & Evidence