HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 21101722, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Reactant | 3-Fluoro-4-methoxyaniline | HCID 581110 | — |
| Reactant | 7-Chloro-4-(piperazin-1-yl)quinoline | HCID 738389 | — |
| Product | HCID 21101722 | HCID 21101722 | — |
Reaction Steps
As described for example 78, 4-methoxy-3-fluoro-aniline, p-nitrophenyl chloroformate, diisopropylethyl amine, and 7-chloro-4-piperazinylquinoline are reacted to afford the product. LC-MS: 415 (M++1). 1H NMR (CDCl3) δ 8.78 (d, 1H), 8.05 (s, 1H), 7.95 (d, 1H), 7.50 (d, 1H), 7.35 (d, 1H), 7.00 (m, 1H), 6.85 (d, 1H), 6.70 (m, 1H), 6.60 (s, 1H), 3.85 (s, 3H), 3.78 (m, 4H), 3.25 (m, 4H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-40d2d06df8e146ada05c3072315565f0 |
| Source note | uspto-grants-2007_05 |