HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-methoxyaniline → HCID 21101719, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-methoxyaniline | HCID 21441 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Reactant | 7-Chloro-4-(piperazin-1-yl)quinoline | HCID 738389 | — |
| Product | HCID 21101719 | HCID 21101719 | — |
Reaction Steps
As described for example 78, 4-methoxy-3-chloro-aniline, p-nitrophenyl chloroformate, diisopropylethyl amine, and 7-chloro-4-piperazinylquinoline are reacted to afford the product. LC-MS: 431 (M++1). 1H NMR (CDCl3) δ 8.78 (d, 1H), 8.05 (s, 1H), 7.95 (d, 1H), 7.50 (d, 1H), 7.45 (s, 1H), 7.22 (d, 1H), 6.90 (m, 2H), 6.38 (s, 1H), 3.85 (s, 3H), 3.80 (m, 4H), 3.25 (m, 4H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220856B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-afd5604870564e0b9096fba0d2eb1fba |
| Source note | uspto-grants-2007_05 |