4-Methylphenyl isocyanate → HCID 21101678, compound

Participants

Reaction Steps

As described for example 159, 7-chloro-4-(1-piperazinyl)-2-quinolinamine, 4-methylphenyl isocyanate, and diisopropylethyl amine, are reacted to give the product as a white solid. LC-MS: 395 (M++1). 1H NMR (DMSO-d6) δ 2.25 (s, 3H), 3.0–3.1 (m, 4H), 3.64–3.75 (m, 4H), 6.3 (s, 1H), 6.5 (s, 2H), 7.0–7.1 (d, 2H), 7.1–7.2 (m, 1H), 7.3–7.45 (m, 3H), 7.75–7.85 (d, 1H), 8.5–8.6 (s, 1H).

Provenance & Evidence