Acetic acid, 2-isothiocyanato-, ethyl ester → HCID 58864169, compound

Participants

Reaction Steps

As described for example 159, 7-chloro-4-(1-piperazinyl)-2-quinolinamine, isothiocyanato-acetic acid-ethy ester, and diisopropylethyl amine, are reacted to give the product as a white solid. LC-MS: 407 (M++1). 1H NMR (DMSO-d6): δ 1.16 (t, 3H), 3.05 (br.s, 4H), 4.01 (br.s, 4H), 4.06 (q, 2H), 4.20 (d, 2H), 6.24 (s, 1H), 6.47 (br.s, 2H), 7.08 (dd, 1H), 7.36 (d, 1H), 7.76 (d, 1H), 8.23 (dd, 1H).

Provenance & Evidence