Hydrochloric Acid → HCID 58864166, compound

Participants

Reaction Steps

A mixture of (2S)-2-[[[4-(2-amino-7-chloro-4-quinolinyl)-1-piperazinyl]carbonyl]amino]-propanoic acid-methyl ester (˜50 mg, 0.13 mmol), LiOH (100 mg) in THF-H2O (5 mL, 5:1) was stirred at rt for 3 h. The mixture was diluted with H2O, and acidified with 1.0 N HCl to pH˜5. The crude acid was obtained as a white solid by filtration.

Provenance & Evidence