Diisopropylethylamine → HCID 10388235, compound

Participants

Reaction Steps

As described for example 78, (6S)-6-aminotetrahydro-1,4-thiazepin-5(2H)-one, p-nitrophenyl chloroformate, diisopropylethyl amine, and 7-chloro-4-(1-piperazinyl)-2-quinolinamine are reacted to afford the product. LC-MS: 434 (M++1). 1H NMR (CDCl3) δ 2.55–2.95 (m, 4), 3.0–3.25 (m, 4H), 3.6–3.9 (m, 6H), 4.8–5.0 (m, 3H), 6.1–6.2 (s, 1H), 6.2–6.4 (m, 2H), 7.1–7.24 (m, 1H), 7.6 (s, 1H), 7.7–7.8 (m, 1H).

Provenance & Evidence