Diisopropylethylamine → HCID 58864153, compound

Participants

Reaction Steps

As described for example 78, (3R)-1-acetylhexahydro-1H-azepin-3-amine, 4-nitrophenyl chloroformate, diisopropyl(ethyl)amine, and 7-chloro-4-(1-piperazinyl)-2-quinolinamine are reacted to afford the product as a light yellow solid. LC-MS: 445 (M++1). 1H NMR (CDCl3) δ 7.70 (d, 1H), 7.60 (s, 1H), 7.15 (d, 1H), 6.02 (s, 1H), 4.70 (s, 2H), 4.22 (d, 1H), 4.10 (m, 1H), 3.92 (m, 1H), 3.60 (m, 4H), 3.10 (m, 6H), 2.25 (m, 1H), 2.15 (s, 3H), 1.60–1.90 (m, 3H), 1.30–1.40 (m, 2H).

Provenance & Evidence