Trifluoroacetic acid → HCID 69515070, compound

Participants

Reaction Steps

As described for example 213, [(3R)-hexahydro-1-[(methylamino)carbonyl]-2-oxo-1H-azepin-3-yl]-carbamic acid-1,1-dimethylethyl ester, TFA, K2CO3 (sat.) 7-chloro-4-(1-piperazinyl)-2-quinolinamine are reacted to afford the product. 1H NMR (DMSO-d6): δ 1.2 (m, 1H), 1.6 (m, 1H), 1.71 (m, 2H), 1.84 (m, 2H), 2.73 (s, 3H), 2.98 (m, 4H), 3.31 (m, 2H), 3.58 (m, 4H), 4.57 (m, 1H), 4.64 (t, 1H), 6.22 (s, 1H), 6.45 (br. s, 1H), 6.78 (d, 1H), 7.11 (d, 1H), 7.37 (s, 1H), 7.76 (d, 1H), 8.84 (m, 1H).

Provenance & Evidence