HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(1-Benzothiophen-3-yl)prop-2-enoic acid → 3-(1-Benzothiophen-3-yl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(1-Benzothiophen-3-yl)prop-2-enoic acid | HCID 53427004 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethylacetate methanol | HCID 21584119 | — |
| Product | 3-(1-Benzothiophen-3-yl)propanoic acid | HCID 12318983 | — |
Reaction Steps
A suspension of 3-benzo[b]thiophen-3-yl-acrylic acid: (5.6 g, 0.027 mol) and 10% Pd/C (600 mg) in 1:1 methanol/ethyl acetate (50 mL) was hydrogenated in a Parr apparatus at 50 psi overnight. The mixture was filtered and concentrated to give the crude product without further purification (ca. 100% conversion). Mass spec.: 205(MH)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07220862B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-7ca4042a9670419d8623962d5ca649a4 |
| Source note | uspto-grants-2007_05 |