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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 135403Generated: October 30, 2026

1,4'-Bipiperidine → 2-[[4-Amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione

https://huagongshe.com/reaction/135403

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4'-BipiperidineHCID 78607—
Reactant2-(4-amino-3-chloro-5-trifluoromethyl-benzyl)-4-oxo-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butanoic acidHCID 12094449—
Product2-[[4-Amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dioneHCID 12094441—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-b87455e072264ad6925e59760f22f8b5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)