1-(2,3-Dichlorophenyl)piperazine → HCID 11952879, compound

HRID 1354071Notes

Reaction equation

HRID 1354071 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1.[Cl:15][C:16]1[CH:24]=[C:23]2[C:19]([C:20]([CH2:25][CH2:26][CH2:27]I)=[CH:21][NH:22]2)=[CH:18][CH:17]=1>>[Cl:15][C:16]1[CH:24]=[C:23]2[C:19]([C:20]([CH2:25][CH2:26][CH2:27][N:12]3[CH2:13][CH2:14][N:9]([C:3]4[CH:4]=[CH:5][CH:6]=[C:7]([Cl:8])[C:2]=4[Cl:1])[CH2:10][CH2:11]3)=[CH:21][NH:22]2)=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 8518331-(2,3-Dichlorophenyl)piperazineHCID 22029312HCID 22029312, compound

Product 1

HCID 11952879HCID 11952879, compound

Procedure

from 1-(2,3-dichlorophenyl)piperazine and 6-chloro 3-(3-iodopropyl)-1H-indole. 1H NMR (CDCl3): 1.95 (t, 2H); 2.55 (t, 2H); 2.65 (b s, 4H); 2.80 (t, 2H); 3.10 (b s, 4H); 6.95–7.05 (m, 2H); 7.10 (d, 1H); 7.10–7.20 (m, 2H); 7.35 (s, 1H); 7.55 (d, 1H); 7.95 (b s, 1H). Ms m/z: 422 (MH+), 424.

Sources & evidence

ORD record
ord-8e756f21ab0648a39ae9803131303e93
Source dataset
uspto-grants-2007_05
Patent number
US07223765B2

Reaction notes

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