HCID 58866148, compound → HCID 58866171, compound

Participants

Reaction Steps

The above compound (5-2) (100 mg) was dissolved in a solvent mixture of 1,4-dioxane/methanol (5–15 mL) and a cation exchange resin (Muromac, 2.5 g) was added, and then the mixture was stirred at room temperature for 14 hours. The insoluble material was removed by filtration and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel medium pressure column chromatography (chloroform:methanol=20:1→10:1) to obtain the titled compound (88 mg).

Provenance & Evidence