Methanol → HCID 21104867, compound

Participants

Reaction Conditions

Reaction Steps

The above compound (6) (6.0 g) was dissolved in methanol (180 mL) and 10% Pd—C (1.3 g) was added, and then the mixture was stirred under a hydrogen atmosphere at 45° C. for 2 hours and 30 minutes. The catalyst was removed by filtration and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel medium pressure column chromatography (chloroform:methanol=20:1→10:1→5:1) to obtain the titled compound (3.76 g) as a colorless powder.

Provenance & Evidence