HCID 58866156, compound → HCID 58866164, compound

Participants

Reaction Steps

The above compound (7) (278 mg) was dissolved in ethyl acetate (15 mL) and 10% Pd—C (38 mg) was added, and then the mixture was stirred under a hydrogen atmosphere room temperature for 2 hours. The catalyst was removed by filtration and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel medium pressure column chromatography (chloroform:methanol=50:1→30:1→10:1) and then freeze-dried to obtain the titled compound (205 mg) as a colorless amorphous.

Provenance & Evidence