Ethyl Acetate → HCID 58866130, compound

Participants

Reaction Steps

The above compound (2-1) (670 mg) was dissolved in acetonitrile (30 mL) and cesium acetate (0.5 g) and 18-Crown-6 (1.4 g) were added, and then the mixture was stirred at room temperature for 16 hours, To the reaction solution was added ethyl acetate (100 mL) and, after washing in turn with dilute hydrochloric acid, an aqueous saturated sodium hydrogencarbonate solution and saturated saline, the solution was dried over magnesium sulfate and the solvent was distilled off under reduced pressure. The resulting residue was purified by silica gel column chromatography (ethyl acetate:n-hexane=1:3→1:1) to obtain the titled compound (161 mg).

Provenance & Evidence