Sodium Methoxide → HCID 58866159, compound

Participants

Reaction Steps

The above compound (2-2) (100 mg) was dissolved in methanol (2 mL) and 28% sodium methoxide (18 mg) was added, and then the mixture was stirred at room temperature for 2 hours. After neutralizing with a cation exchange resin, the insoluble material was removed by filtration and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (ethyl acetate:n-hexane=1:2→1:1→2:1) to obtain the titled compound (69 mg).

Provenance & Evidence