HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1354296Generated: October 31, 2026
Hydrochloric Acid → HCID 136008000, compound
https://huagongshe.com/reaction/1354296
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | N-(4-Cyano-1,3-dimethyl-1H-pyrazol-5-yl)-2-fluorobenzamide | HCID 17088883 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 136008000 | HCID 136008000 | 67% |
Reaction Steps
N-(4-Cyano-2,5-dimethyl-2H-pyrazol-3-yl)-2-fluoro-benzamide (5.0 g, 19.36 mmole) was suspended in 38 ml 1M sodium hydroxide and heated to 90° C. for 3 hours followed by addition of 30% hydrogen peroxide (10 ml) and further heating overnight. Cooled reaction mixture to room temperature and acidified with dilute hydrochloric acid. Product was isolated by filtration, washed with water, and dried overnight under vacuum to obtain 3.39 g product. (Yield 67%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07223766B2 |
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| Source dataset | uspto-grants-2007_05 |
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| ORD ID | ord-dd88d719332c495bb87c218ac13abb89 |
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| Source note | uspto-grants-2007_05 |
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