化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 2,4'-Dichloroacetanilide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Chloroacetyl chloride | HCID 6577 | — |
| 反応物 | 4-Chloroaniline | HCID 7812 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 2,4'-Dichloroacetanilide | HCID 94920 | — |
反応手順
3.4 g (30 mol) of 2-chloroacetyl chloride were dissolved in anhydrous dioxane and a solution containing 3.8 g (30 mol) of 4-chloroaniline was added dropwise. After an hour, the batch was poured into ice water, acidified using dilute hydrochloric acid, the supernatant was removed by suction and the residue was washed with water until neutral. The reaction product was recrystallized from ethanol. The yield was 3.2 g.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07223781B2 |
| 出典データセット | uspto-grants-2007_05 |
| ORD ID | ord-adf3d798277641cc8b923af5e83e894e |
| 出典メモ | uspto-grants-2007_05 |