Sodium Hydroxide → HCID 21105705, compound

HRID 1354361Notes

Reaction equation

HRID 1354361 reaction equation
C[O:2][C:3]([C:5]1[C:17]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([N+:18]([O-:20])=[O:19])[CH:15]=3)[N:10]([CH3:21])[C:9]=2[C:8]([O:22][CH3:23])=[CH:7][CH:6]=1)=[O:4].[OH-].[Na+]>CO>[CH3:23][O:22][C:8]1[C:9]2[N:10]([CH3:21])[C:11]3[C:16](=[CH:15][C:14]([N+:18]([O-:20])=[O:19])=[CH:13][CH:12]=3)[C:17]=2[C:5]([C:3]([OH:4])=[O:2])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 21105716HCID 21105716, compound

Product 1

HCID 21105705HCID 21105705, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Methyl-1-methoxy-9-methyl-6-nitro-9H-4-carbazolecarboxylate (500 mg) was suspended in methanol (15 ml) and added with 1 M NaOH (10 ml). The reaction mixture was refluxed for 18 hrs. Methanol was evaporated and the compound was diluted with water followed by addition of HCl. The precipitate was filtered to get a brown solid.

Workup

  1. temperatureThe reaction mixture was refluxed for 18 hrs
  2. customMethanol was evaporated
  3. additionthe compound was diluted with water
  4. additionfollowed by addition of HCl
  5. filtrationThe precipitate was filtered
  6. customto get a brown solid

Sources & evidence

ORD record
ord-e1ac49c075bd4488a53375346e78b059
Source dataset
uspto-grants-2007_05
Patent number
US07223789B2

Reaction notes

Loading…