HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → 4-Methylbenzene-1-sulfonic acid--(3S)-3-aminooxetan-2-one (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | N-[tert-butoxycarbonyl]-L-serine | HCID 98766 | — |
| Reactant | Diethyl azodicarboxylate | HCID 5462977 | — |
| Product | 4-Methylbenzene-1-sulfonic acid--(3S)-3-aminooxetan-2-one (1/1) | HCID 15600537 | — |
Reaction Steps
Boc serine is treated with Ph3P, DEAD, and TFA , followed by TsOH to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07223833B1 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-a1ec8e1e4260499e80d0d9fb3767e1e0 |
| Source note | uspto-grants-2007_05 |