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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 135458Generated: October 30, 2026

Diethyl Ether → 5-Hydroxy-5-[3-(4-trifluoromethylphenyl)phenyl]hexanenitrile

https://huagongshe.com/reaction/135458

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantTetrahydrofuranHCID 8028—
ReactantHexanenitrile, 5-oxo-HCID 82611—
Reactant3-Bromo-4'-(trifluoromethyl)-1,1'-biphenylHCID 19955458—
ReactantButyllithiumHCID 178418339—
Product5-Hydroxy-5-[3-(4-trifluoromethylphenyl)phenyl]hexanenitrileHCID 19955512—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-178ac7b5193b43a587ec8d66f85cd488
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)