HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → tert-Butyl (R)-methyl-[1-(4-nitrophenyl)pyrrolidin-3-yl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | tert-butyl [(3R)-1-(4-nitrophenyl)pyrrolidin-3-yl]carbamate | HCID 86594863 | — |
| Product | tert-Butyl (R)-methyl-[1-(4-nitrophenyl)pyrrolidin-3-yl]carbamate | HCID 67148139 | — |
Reaction Steps
tert-Butyl (R)-[1-(4-nitrophenyl)pyrrolidin-3-yl]carbamate was alkylated with iodomethane by method F. This resulted in the product with the molecular weight of 321.38 (C16H23N3O4); MS (ESI): 322 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07223788B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-04ecbba343294462a3ac8d5ef6803c7e |
| Source note | uspto-grants-2007_05 |