2-Oxo-1,3-thiazolidine-4-carboxylic acid → HCID 131726463, compound

HRID 1354670Notes

Reaction equation

HRID 1354670 reaction equation
[CH3:1][NH:2][C@@H:3]1[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15]([N:17]3[CH2:22][CH2:21][CH:20]([C:23]4[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=4)[CH2:19][CH2:18]3)=[O:16])=[CH:10][CH:9]=2)[CH2:4]1.[O:30]=[C:31]1[NH:35][CH:34]([C:36](O)=[O:37])[CH2:33][S:32]1>>[CH3:1][N:2]([C:36]([C@@H:34]1[CH2:33][S:32][C:31](=[O:30])[NH:35]1)=[O:37])[CH:3]1[CH2:7][CH2:6][N:5]([C:8]2[CH:9]=[CH:10][C:11]([NH:14][C:15]([N:17]3[CH2:18][CH2:19][CH:20]([C:23]4[CH:24]=[CH:25][C:26]([Cl:29])=[CH:27][CH:28]=4)[CH2:21][CH2:22]3)=[O:16])=[CH:12][CH:13]=2)[CH2:4]1

Participants

3

Reactant 2

HCID 652722-Oxo-1,3-thiazolidine-4-carboxylic acidHCID 58867492HCID 58867492, compound

Product 1

HCID 131726463HCID 131726463, compound

Procedure

(R)-4-(4-Chlorophenyl)piperidin-1-carboxylic acid [4-(3-methylamino-pyrrolidin-1-yl)phenyl]amide was reacted with 2-oxothiazolidine-4-carboxylic acid by method E. This resulted in the product with the molecular weight of 542.10 (C27H32ClN5O3S); MS (ESI): 542 (M+H+).

Workup

  1. customThis resulted in the product with the molecular weight of 542.10 (C27H32ClN5O3S)

Sources & evidence

ORD record
ord-9e15734a00fc445480d614873d4977d5
Source dataset
uspto-grants-2007_05
Patent number
US07223788B2

Reaction notes

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