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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1354672Generated: October 26, 2026

Diethylaminoethyl chloride → (R)-N-(2-Diethylaminoethyl)-N-[1-(4-nitrophenyl)pyrrolidin-3-yl]acetamide

https://huagongshe.com/reaction/1354672

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylaminoethyl chlorideHCID 13364—
Reactant(R)-N-[1-(4-Nitrophenyl)pyrrolidin-3-yl]acetamideHCID 67147876—
Product(R)-N-(2-Diethylaminoethyl)-N-[1-(4-nitrophenyl)pyrrolidin-3-yl]acetamideHCID 67147763—

Reaction Steps

(R)-N-[1-(4-nitrophenyl)pyrrolidin-3-yl]acetamide was reacted with 2-chloroethyldiethylamine by method F. This resulted in the product with the molecular weight of 348.45 (C18H28N4O3); MS (ESI): 349 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07223788B2
Source datasetuspto-grants-2007_05
ORD IDord-b5ef2f643f0f43eeb06d4849942b86a2
Source noteuspto-grants-2007_05