HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,1'-Carbonyldiimidazole → N-Methyl-N-(1-{4-[3-(4-piperidin-1-ylphenyl)ureido]phenyl}pyrrolidin-3-yl)acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Edukt | 4-(Piperidin-1-yl)aniline | HCID 413501 | — |
| Edukt | N-[1-(4-aminophenyl)pyrrolidin-3-yl]-N-methylacetamide | HCID 21105566 | — |
| Produkt | N-Methyl-N-(1-{4-[3-(4-piperidin-1-ylphenyl)ureido]phenyl}pyrrolidin-3-yl)acetamide | HCID 21105625 | — |
Reaktionsschritte
N-[1-(4-Aminophenyl)pyrrolidin-3-yl]-N-methylacetamide was reacted with carbonyldiimidazole and then with 4-piperidin-1-ylphenylamine by method A. This resulted in the product with the molecular weight of 435.57 (C25H33N5O2); MS (ESI): 436 (M+H+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07223788B2 |
| Quelldatensatz | uspto-grants-2007_05 |
| ORD ID | ord-aa7b3a8e69d8404bb190dc9c09c68c8f |
| Quellennotiz | uspto-grants-2007_05 |