1-Bromo-2-methylpropane → HCID 21105582, compound

HRID 1354692Notes

Reaction equation

HRID 1354692 reaction equation
[C:1]([CH2:4][NH:5][CH:6]1[CH2:10][CH2:9][N:8]([C:11]2[CH:16]=[CH:15][C:14]([NH:17][C:18](=[O:27])[CH2:19][C:20]3[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=3)=[CH:13][CH:12]=2)[CH2:7]1)(=[O:3])[CH3:2].[CH2:28](Br)[CH:29]([CH3:31])[CH3:30]>>[C:1]([CH2:4][NH:5][CH:6]1[CH2:10][CH2:9][N:8]([C:11]2[CH:12]=[CH:13][C:14]([NH:17][C:18](=[O:27])[CH2:19][C:20]3[CH:21]=[CH:22][C:23]([O:26][CH2:28][CH:29]([CH3:31])[CH3:30])=[CH:24][CH:25]=3)=[CH:15][CH:16]=2)[CH2:7]1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 65551-Bromo-2-methylpropaneHCID 21105580HCID 21105580, compound

Product 1

HCID 21105582HCID 21105582, compound

Procedure

N-{4-[3-(Acetylmethylamino)pyrrolidin-1-yl]phenyl}-2-(4-hydroxyphenyl)acetamide was reacted with isobutyl bromide by method H. This resulted in the product with the molecular weight of 423.56 (C25H33N3O3); MS (ESI): 424 (M+H+).

Workup

  1. customThis resulted in the product with the molecular weight of 423.56 (C25H33N3O3)

Sources & evidence

ORD record
ord-91bda38cc6744572a931a751bbf2ed46
Source dataset
uspto-grants-2007_05
Patent number
US07223788B2

Reaction notes

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