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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1354713Generated: October 29, 2026

5-Bromo-2-furanecarboxylic acid → 5-Bromofuran-2-carboxylic Acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide

https://huagongshe.com/reaction/1354713

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-furanecarboxylic acidHCID 68511—
Reactant1-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amineHCID 21916591—
Product5-Bromofuran-2-carboxylic Acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amideHCID 67147759—

Reaction Steps

[1-(4-Aminophenyl)pyrrolidin-3-yl]dimethylamine was reacted with 5-bromo-2-furancarboxylic acid by method E. The product with a molecular weight of 378.27 (C17H20BrN3O2); MS (ESI): 379 (M+H+) was obtained as hydrotrifluoroacetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07223788B2
Source datasetuspto-grants-2007_05
ORD IDord-1137ca5749ec47d4ab9f83108772b3bf
Source noteuspto-grants-2007_05