HCID 21105428, compound → HCID 21105607, compound

HRID 1354723Notes

Reaction equation

HRID 1354723 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N:11]1[CH2:16][CH2:15][CH:14]([CH3:17])[CH2:13][CH2:12]1)[C:5]([OH:7])=O.[NH2:18][C:19]1[CH:24]=[CH:23][C:22]([N:25]2[CH2:29][CH2:28][CH:27]([N:30]([CH3:32])[CH3:31])[CH2:26]2)=[CH:21][CH:20]=1>>[CH3:31][N:30]([CH3:32])[CH:27]1[CH2:28][CH2:29][N:25]([C:22]2[CH:23]=[CH:24][C:19]([NH:18][C:5](=[O:7])[C:4]3[CH:8]=[CH:9][C:10]([N:11]4[CH2:16][CH2:15][CH:14]([CH3:17])[CH2:13][CH2:12]4)=[C:2]([F:1])[CH:3]=3)=[CH:20][CH:21]=2)[CH2:26]1

Participants

3

Reactant 2

HCID 21105428HCID 21105428, compoundHCID 219165911-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amine

Product 1

HCID 21105607HCID 21105607, compound

Procedure

3-Fluoro-4-(4-methylpiperidin-1-yl)benzoic acid was reacted with [1-(4-aminophenyl)-pyrrolidin-3-yl]dimethylamine by method E-a. This resulted in the product with the molecular weight of 424.00 (C25H33FN4O); MS (ESI): 425 (M+H+) as hydrotrifluoroacetate.

Workup

  1. customThis resulted in the product with the molecular weight of 424.00 (C25H33FN4O)

Sources & evidence

ORD record
ord-59674eff9a074595a80cdbbc6eb3c401
Source dataset
uspto-grants-2007_05
Patent number
US07223788B2

Reaction notes

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