HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-fluoropyridine → N-[4-(3-Dimethylaminopyrrolidin-1-yl)phenyl]-4-(5-fluoropyridin-2-yloxy)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-fluoropyridine | HCID 2782801 | — |
| Reactant | N-[4-(3-dimethylaminopyrrolidin-1-yl)phenyl]-4-hydroxybenzamide | HCID 21105609 | — |
| Product | N-[4-(3-Dimethylaminopyrrolidin-1-yl)phenyl]-4-(5-fluoropyridin-2-yloxy)benzamide | HCID 21105608 | — |
Reaction Steps
2-Chloro-5-fluoropyridine was reacted with N-[4-(3-dimethylaminopyrrolidin-1-yl)phenyl]-4-hydroxybenzamide by method R. This resulted in the product with the molecular weight of 420.2 (C24H25FN4O2); MS (ESI): 421 (M+H+) as hydrotrifluoroacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07223788B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-4eb22d3503c749e0ac0d81f26c31daed |
| Source note | uspto-grants-2007_05 |