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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1354756Generated: November 2, 2026

Bromomethylcyclopropane → HCID 58867422, compound

https://huagongshe.com/reaction/1354756

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromomethylcyclopropaneHCID 81503—
ReactantHCID 67148105HCID 67148105—
ReactantHCID 67148281HCID 67148281—
ProductHCID 58867422HCID 58867422—

Reaction Steps

(R)-4-Benzyloxy-N-[4-(3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]benzamide underwent debenzylating hydrogenation by method B. The resulting (R)-N-[4-(3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-4-hydroxybenzamide was alkylated with cyclopropylmethyl bromide by method H. This resulted in the product with the molecular weight of 397.50 (C23H28N3O2); MS (ESI): 398 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07223788B2
Source datasetuspto-grants-2007_05
ORD IDord-8f7fad16e3a242c8bdd443a048ace7b2
Source noteuspto-grants-2007_05