p-Fluoronitrobenzene → 1-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amine

HRID 1354765Notes

Reaction equation

HRID 1354765 reaction equation
[CH3:1][N:2]([CH3:8])[CH:3]1[CH2:7][CH2:6][NH:5][CH2:4]1.F[C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=1>>[NH2:16][C:13]1[CH:14]=[CH:15][C:10]([N:5]2[CH2:6][CH2:7][CH:3]([N:2]([CH3:8])[CH3:1])[CH2:4]2)=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 9590p-FluoronitrobenzeneHCID 27585193-(Dimethylamino)pyrrolidine

Product 1

HCID 219165911-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amine

Procedure

Dimethylpyrrolidin-3-ylamine was reacted with 4-fluoronitrobenzene by method C, and the product was subsequently hydrogenated by method B. This resulted in the product with the molecular weight of 205.31 (C12H19N3); MS (ESI): 206 (M+H+).

Workup

  1. customThis resulted in the product with the molecular weight of 205.31 (C12H19N3)

Sources & evidence

ORD record
ord-3bc91b2f3ff043c090ab13a31a3ac2cc
Source dataset
uspto-grants-2007_05
Patent number
US07223788B2

Reaction notes

Loading…