HCID 21105435, compound → HCID 18695463, compound

HRID 1354789Notes

Reaction equation

HRID 1354789 reaction equation
[F:1][C:2]1[CH:17]=[C:16]([F:18])[CH:15]=[CH:14][C:3]=1[O:4][C:5]1[CH:13]=[CH:12][C:8]([C:9]([OH:11])=[O:10])=[CH:7][CH:6]=1.N[C:20]1C=CC(N2CCC(N(C)C)C2)=C[CH:21]=1>>[F:1][C:2]1[CH:17]=[C:16]([F:18])[CH:15]=[CH:14][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([C:9]([O:11][CH2:20][CH3:21])=[O:10])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 21105435HCID 21105435, compoundHCID 219165911-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amine

Product 1

HCID 18695463HCID 18695463, compound

Procedure

4-(2,4-Difluorophenoxy)benzoic acid was reacted with [1-(4-aminophenyl)pyrrolidin-3-yl]-dimethylamine by method E-b. This resulted in the product with the molecular weight of 437.19 (C25H25F2N3O2); MS (ESI): 438 (M+H+) as hydrotrifluoroacetate.

Workup

  1. customThis resulted in the product with the molecular weight of 437.19 (C25H25F2N3O2)

Sources & evidence

ORD record
ord-f7a025f325784993b58fa9ce02f273c6
Source dataset
uspto-grants-2007_05
Patent number
US07223788B2

Reaction notes

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