HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminobenzamide → 4-(3,5-Dimethylphenylamino)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminobenzamide | HCID 76079 | — |
| Reactant | 3,5-Dimethylphenyl benzenesulfonate | HCID 11242472 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-(3,5-Dimethylphenylamino)benzamide | HCID 11333920 | 96% |
Reaction Steps
Following the general procedure, 3,5-dimethylphenyl benzenesulfonate (131 mg, 0.5 mmol) was coupled with 4-aminobenzamide (102 mg, 0.75 mmol) with the reaction time of 6 h. Chromatography on silica gel column with ethyl acetate gave 115 mg (96%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07223879B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-244f0c4ccb664548b3566499484ad9cf |
| Source note | uspto-grants-2007_05 |