HuagongsheHuagongshe Chemistry Print Report · For research reference only
Anthranilamide → 2-(4-Cyanophenylamino)Benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Anthranilamide | HCID 6942 | — |
| Reactant | Hexane | HCID 8058 | — |
| Reactant | Benzonitrile, 4-bromo- | HCID 12162 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-(4-Cyanophenylamino)Benzamide | HCID 21106123 | 87% |
Reaction Steps
Following the general procedure, 4-bromobenzonitrile (91 mg, 0.5 mmol) was coupled with 2-aminobenzamide (102 mg, 0.75 mmol) with the reaction time of 17 h. Chromatography on silica gel column with 1:1 hexane:ethyl acetate gave 103 mg (87%) of the title compound as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07223879B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-d59c3353d4a04c52930797418b77a83c |
| Source note | uspto-grants-2007_05 |