HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → N-(3,5-dimethylphenyl)-N-methylformamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | N-Methylformamide | HCID 31254 | — |
| Reactant | 3,5-Dimethylphenyl benzenesulfonate | HCID 11242472 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-(3,5-dimethylphenyl)-N-methylformamide | HCID 9855564 | 93.1% |
Reaction Steps
Following the general procedure, 3,5-dimethylphenyl benzenesulfonate (131 mg, 0.5 mmol) was coupled with N-methylformamide (45 mg, 0.75 mmol) with the reaction time of 20 h. Chromatography on silica gel column with 4:1 hexane:ethyl acetate gave 76 mg (93%) of the title compound as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07223879B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-9c04008732b44dffaf88cf7e7f80f9c3 |
| Source note | uspto-grants-2007_05 |