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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1354975Generated: November 1, 2026

Benzamide → N-1-Naphthylbenzamide

https://huagongshe.com/reaction/1354975

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzamideHCID 2331—
ReactantHexaneHCID 8058—
ReactantHCID 1796834HCID 1796834—
SolventEthyl AcetateHCID 8857—
ProductN-1-NaphthylbenzamideHCID 6944895%

Reaction Steps

Following the general procedure, 1-naphthyl tosylate (149 mg, 0.5 mmol) was coupled with benzamide (90 mg, 0.75 mmol) with the reaction time of 20 h. Chromatography on silica gel column with 4:1 hexane:ethyl acetate gave 117 mg (95%) of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07223879B2
Source datasetuspto-grants-2007_05
ORD IDord-1e653f37333641c18514bdf8639e2612
Source noteuspto-grants-2007_05