HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Amino-2-propanol → HCID 9901790, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Amino-2-propanol | HCID 4 | — |
| Reactant | HCID 18506776 | HCID 18506776 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 9901790 | HCID 9901790 | — |
Reaction Steps
In analogy to the procedure as described in example 4 the 3-methylsulfanyl-5-(1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-[1,2,4]triazine-6-carbonitrile was reacted with (RS)-1-amino-2-propanol in dioxane at 120° C. overnight to give (RS)-3-(2-hydroxy-propylamino)-5-(1,2,4,5 -tetrahydro-benzo[d]azepin-3-yl)-[1,2,4]triazine-6-carbonitrile as a white solid; MS: 325 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586422B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-78b6a1711c0a42e88eb5c55cb64a06b5 |
| Source note | uspto-grants-2003_07 |