HCID 59743051, compound → HCID 69153789, compound

HRID 1355417Notes

Reaction equation

HRID 1355417 reaction equation
[CH2:1]([O:3][CH2:4][N:5]1[C:9]2=[N:10][C:11]3[N:12]([CH3:26])[C:13](=[O:25])[N:14]([CH2:18][CH2:19][CH2:20][CH2:21][C@H:22]([OH:24])[CH3:23])[C:15](=[O:17])[C:16]=3[N:8]2[CH2:7][CH2:6]1)[CH3:2].C(O[C@@H](C)CCCCCl)(=O)C>>[CH2:1]([O:3][CH2:4][N:5]1[C:9]2=[N:10][C:11]3[N:12]([CH3:26])[C:13](=[O:25])[N:14]([CH2:18][CH2:19][CH2:20][CH2:21][C@@H:22]([OH:24])[CH3:23])[C:15](=[O:17])[C:16]=3[N:8]2[CH2:7][CH2:6]1)[CH3:2]

Participants

3

Reactant 2

HCID 59743051HCID 59743051, compoundHCID 69155336HCID 69155336, compound

Product 1

HCID 69153789HCID 69153789, compound

Procedure

(S)-7,8-dihydro-8-ethoxymethyl-3-(5-hydroxyhexyl)-1-methyl-1H-imidazo[2,1-f]-purine-2,4(3H,6H)-dione was prepared according to the method described for the synthesis of (R)-7,8-dihydro-8-ethoxymethyl-3-(5-hydroxyhexyl)-1-methyl-1H-imidazo[2,1-f]-purine-2,4(3H,6H)-dione but using (S)-5-acetoxy-1-chlorohexane in place of (R)-5-acetoxy-1-chlorohexane.

Sources & evidence

ORD record
ord-b577dd414f194b8e84b184798a5102e9
Source dataset
uspto-grants-2003_07
Patent number
US06586429B2

Reaction notes

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