HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86759042, compound → HCID 178462168, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86759042 | HCID 86759042 | — |
| Reactant | HCID 86759043 | HCID 86759043 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | HCID 178462168 | HCID 178462168 | 66% |
Reaction Steps
A solution benzylsulfonyl-D-serine-L-alanine-(4-(N-tert-butoxycarbonylguanidino) benzylamide (7-5) (9.0 mg, 0.016 mmol), in a mixture of CH2Cl2/TFA (1:1, 600 μl) was stirred at room temperature for 90 minutes. The solvent was removed in vacuo to give a transparent oil. HPLC purification (CH3CN, H2O, 0.1% TFA) gave a fluffy white solid as the title compound (5.0 mg, 66%), MS (electrospray) 477 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586405B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-cca3ae7f413941a2b6f80144bb536d0d |
| Source note | uspto-grants-2003_07 |