HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → 7-bromo-3,4-dihydro-1H-2-benzopyran-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 5-Bromo-2-(carboxymethyl)benzoic acid | HCID 10634987 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 7-bromo-3,4-dihydro-1H-2-benzopyran-1,3-dione | HCID 18507796 | — |
Reaction Steps
To the title compound of 16A in acetonitrile (CH3CN, 60 ml) was added N,N′-dicyclohexylcarbodiimide (DCC, 5.8 g, 28.2 mmol). The reaction mixture was stirred at ambient temperature overnight. After filtration, the filtrate was evaporated to give the title compound of 16B as a yellow solid (96.32 g, 98.7% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586447B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-621f5b034bb04ebd9b39217eb04a16cc |
| Source note | uspto-grants-2003_07 |