反应详情

To a solution of 3-bromobenzylbromide (15.0 g) in methanol-dimethoxyethane (30 ml+10 ml) was added sodium methylate (4.9 g) under cooling with ice and the mixture was stirred for 1 hour at room temperature. The reaction mixture was poured into water. The reaction mixture was extracted with ether. The organic layer was washed with a saturated aqueous solution of sodium chloride, dried over anhydrous magnesium sulfate and the solvent was evaporated to give the title compound (12.1 g) having the following physical data.

1. temperatureunder cooling with ice
2. extractionThe reaction mixture was extracted with ether
3. washThe organic layer was washed with a saturated aqueous solution of sodium chloride
4. dry with materialdried over anhydrous magnesium sulfate
5. customthe solvent was evaporated