HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → HCID 18507379, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Guanidine Nitrate | HCID 10481 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Oxo-3-(3,4,5-trimethoxyphenyl)propanenitrile | HCID 18507691 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Carbon Disulfide | HCID 6348 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 18507379 | HCID 18507379 | — |
Reaction Steps
From 3,4,5-trimethoxybenzoylacetonitrile with sodium hydride, carbon disulphide and methyl iodide in DMSO. Then treatment with guanidine nitrate and triethylamine in DMF. EI-MS m/e (%): 332 (M+, 100), 317 ([M—CH3]+, 36).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-8072d70beecb4dfba910a3024e07beed |
| Source note | uspto-grants-2003_07 |