HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic acid, 2-chloro-, phenylmethyl ester → (2-Amino-5-cyano-6-phenyl-pyrimidin-4-ylsulfanyl)-acetic acid benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic acid, 2-chloro-, phenylmethyl ester | HCID 8786 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 178509378 | HCID 178509378 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (2-Amino-5-cyano-6-phenyl-pyrimidin-4-ylsulfanyl)-acetic acid benzyl ester | HCID 69783167 | — |
Reaction Steps
From 2-amino-4-phenyl-6-thioxo-1,6-dihydro-pyrimidine-5-carbonitrile, benzyl chloroacetate and sodium methylate in methanol. ES-MS m/e (%): 399 (M+Na+, 40), 377 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-4d2ed41b180142c6b3c7724465a3aba5 |
| Source note | uspto-grants-2003_07 |