1,2-Ethanediamine, N1-phenyl- → 2-Amino-4-furan-2-yl-6-(2-phenylamino-ethylamino)-pyrimidine-5-carbonitrile

HRID 1355812Notes

Reaction equation

HRID 1355812 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)(=O)=O)[N:3]=1.[C:19]1([NH:25][CH2:26][CH2:27][NH2:28])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([NH:28][CH2:27][CH2:26][NH:25][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[N:3]=1

Participants

4

Reactant 2

HCID 742701,2-Ethanediamine, N1-phenyl-HCID 185073992-Amino-4-furan-2-yl-6-methanesulfonyl-pyrimidine-5-carbonitrile

Product 1

HCID 98582502-Amino-4-furan-2-yl-6-(2-phenylamino-ethylamino)-pyrimidine-5-carbonitrile

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfonyl-pyrimidine-5-carbonitrile and N-phenylethylenediamine in DME. ES-MS m/e (%): 321 (M+H+, 100).

Sources & evidence

ORD record
ord-1ea9bec5c3f549a0bb2847ff87848825
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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