N-Iodosuccinimide → 4-Furan-2-yl-5-iodo-6-methylsulfanyl-pyrimidin-2-ylamine

HRID 1355820Notes

Reaction equation

HRID 1355820 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:11]=[C:10]([S:12][CH3:13])[N:9]=[C:8]([NH2:14])[N:7]=1.[I:15]N1C(=O)CCC1=O>C(O)(=O)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:11]([I:15])=[C:10]([S:12][CH3:13])[N:9]=[C:8]([NH2:14])[N:7]=1

Participants

4

Reactant 2

HCID 120273N-IodosuccinimideHCID 185076524-Furan-2-yl-6-methylsulfanyl-pyrimidin-2-ylamine

Product 1

HCID 185075894-Furan-2-yl-5-iodo-6-methylsulfanyl-pyrimidin-2-ylamine

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

From 4-furan-2-yl-6-methylsulfanyl-pyrimidin-2-ylamine and N-iodosuccinimide in acetic acid. EI-MS m/e (%): 333 (M+, 66), 206 ([M—I]+, 100), 118 (44).

Sources & evidence

ORD record
ord-160cc336504c436a890d9c62d4f1dc8f
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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