HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 2-Amino-4-furan-2-yl-6-isopropenyl-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | (Prop-1-en-2-yl)boronic acid | HCID 10855372 | — |
| Reactant | Trifluoromethanesulfonic acid 2-amino-5-cyano-6-furan-2-yl-pyrimidin-4-yl ester | HCID 86583747 | — |
| Catalyst | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| Solvent | 1,4-Dioxane--water (1/1) | HCID 21886435 | — |
| Product | 2-Amino-4-furan-2-yl-6-isopropenyl-pyrimidine-5-carbonitrile | HCID 18507350 | — |
Reaction Steps
From trifluoromethanesulfonic acid 2-amino-5-cyano-6-furan-2-yl-pyrimidin-4-yl ester, isopropenylboronic acid, tetrakis(triphenylphosphine)palladium(O) and sodium carbonate in dioxane/water. EI-MS m/e (%): 226 (M+, 74), 225 ([M—H]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-78f482b887cd45f0a547c72756283758 |
| Source note | uspto-grants-2003_07 |