HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethanol → 5-Bromo-4-furan-2-yl-6-(2-methoxy-ethoxy)-pyrimidin-2-yl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethanol | HCID 8019 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 5-Bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-ylamine | HCID 18507286 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-Bromo-4-furan-2-yl-6-(2-methoxy-ethoxy)-pyrimidin-2-yl-amine | HCID 18507536 | — |
Reaction Steps
From 5-bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-yl-amine, 2-methoxyethanol and DBU in dioxane. ES-MS m/e (%): 316 (M{81Br}+H+, 96), 314 (M{79Br}+H+, 100), 258 ([M{81Br}+H-MeOCH═CH2]+, 70), 256 ([M{81Br}+H-MeOCH═CH2]+, 75).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-7e6d9f9af5594254aa64198fd9b1d10c |
| Source note | uspto-grants-2003_07 |